ODCs

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1 OMIM reference -
1 associated gene
No signs/symptoms info

COMMON GENES: 1
PROTEIN INTERACTIONS: 2

2 OMIM references -
4 associated genes
6 signs/symptoms

Autosomal dominant osteopetrosis type 1

Idiopathic juvenile osteoporosis


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	LRP5 LRP5	(0.65) (0.52)	DKK1 WNT1

Citations in the biomedical literature:

Autosomal dominant osteopetrosis type 1		Idiopathic juvenile osteoporosis
	Synonym(s): (no synonyms)		Synonym(s): - IJO - Juvenile osteoporosis

	Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease		Classification (Orphanet): - Rare bone disease - Rare developmental defect during embryogenesis - Rare genetic disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Diseases of the musculoskeletal system and connective tissue -

	Epidemiological data: Class of prevalence: <1 / 1 000 000 Average age onset: adolescence / young Average age of death: normal Type of inheritance: autosomal dominant		Epidemiological data: Class of prevalence: unknown Average age onset: childhood Average age of death: - Type of inheritance: autosomal dominant

	External references: 1 OMIM reference - 1 MeSH reference: C536056		External references: 2 OMIM references - No MeSH references

Idiopathic juvenile osteoporosis
	Very frequent - Bone pain - Mutiple fractures / bone fragility - Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets Frequent - Abnormal gait - Motor deficit / trouble Occasional - Kyphosis
Autosomal dominant osteopetrosis type 1
(no data available)